Documentary filming the work of the neurosurgeons at Oxford's John Radcliffe Hospital over seven months and meeting the patients whose lives depend on their skill.

At Oxford's John Radcliffe Hospital, mum Adele has just heard the devastating news from brain surgeon Jay Jayamohan that her three-year-old daughter Cerys has a malignant brain cancer. This film follows Cerys's battle and shows other patients who are battling similar odds.

The brain is the most complex and mysterious organ in the body and the neurosurgeons of Oxford's John Radcliffe Hospital like Jay Jayamohan deal with brains which go badly wrong.

The parents of two year old Raj face an unimaginable dilemma. Ray has a brain tumour which, untreated, will kill him within months. Doctors at Oxford's John Radcliffe Hospital can operate but the surgery carries a high risk of paralysis.

Dr Kevin Fong finds out how doctors can avoid making mistakes in the high-pressure, high-stakes world of the operating theatre.

Transplant surgery has now reached incredible heights, from achieving full face transplants to growing organs in the lab. This Horizon Guide looks back at the extraordinary odds doctors and patients have had to overcome to achieve these amazing breakthroughs.

A look at people living with OCD, the therapy available and what neuroscience can offer.

Documentary telling the story of Britain's first hand transplant, carried out by surgeons at Leeds Infirmary on Boxing Day night 2012, from the moment Professor Simon Kay and his team decided to go ahead to the moment the patient was able to move the transplanted hand.